aβ42 fitc peptide (Macklin Inc)
86
Structured Review
Macklin Inc
aβ42 fitc peptide
Aβ42 Fitc Peptide, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a%CE%B242+fitc+peptide/a%CE%B242+fitc+peptide/pm41702507-225-4-14
Average 86 stars, based on 1 article reviews
Aβ42 Fitc Peptide, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a%CE%B242+fitc+peptide/a%CE%B242+fitc+peptide/pm41702507-225-4-14
Average 86 stars, based on 1 article reviews
aβ42 fitc peptide - by Bioz Stars,
2026-10
86/100 stars
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other:Article Title: Anti-CLEC7A nanobody in situ engineering promotes amyloid-β oligomers clearance by CAR-microglia to alleviate Alzheimer's disease pathology in mice. Article Snippet: Chimeric antigen receptor microglia (CAR-M)-mediated amyloid-β oligomers (AβO) phagocytosis shows great promise in Alzheimer's disease (AD) treatment, however, the limited AβO degradation of CAR-M compromises their anti-AβO potency.. This work here reports an in situ engineered agonistic anti-C-type lectin domain containing 7 A (CLEC7A) nanobody to accelerate AβO degradation of CAR-M, augmenting their anti-AβO efficacy.. Specifically, with the intranasal-delivered microglia-targeting lipid nanoparticles (LNP), this work generates an AβO-specific degradation-potentiated CAR-M by introducing dual mRNAs encoding AβO-specific CAR and antiCLEC7A nanobody into the cerebral microglia. |